(262) Grumpy Young Men? Factors Associated with Bother in Men with Peyronie’s Disease

Abstract Introduction Age is often correlated with various medical conditions, including bother the condition itself. Peyronie’s disease (PD) a which most associated men in their 50-60’s, however, it does affect younger as well. Anecdotally, PD appear to be more bothered by compared older men. We therefore sought evaluate whether there difference among vs degree of linked PD. Objective To age potential predictor Methods A prospective database has been maintained seeking treatment for Beginning Feb 2020, we began implementing routinely completed standardized intake questionnaires relating PD, Disease Questionnaire (PDQ). The PDQ consists 15 questions broken down into three key subdomains: psychological and physical, penile pain, symptom bother. Men who had questionnaire were evaluated determine correlation between clinicopathologic variables PDQ-bother domain. Results total 645 seen symptoms data available review. Baseline demographics included mean was 51.8 years (SD 17.6), duration 31.3 months 65.3), estimated curve 40.9 degrees 26.8), PDQ-Bother score 8.9 3.1 – Note: lower better). Several clinicopathology found increased scores, (younger = less bothered, parameter estimate -.0.03, p=0.03), presence indentation or hourglass (yes 9.4, no 8.4, p<0.05), pain 9.3, 8.5, p=0.16), preventing penetrative intercourse 9.5, 8.7, p=0.07), shortening p=0.10), subjective erectile dysfunction 9.6, p<0.01), premature ejaculation 9.8, p<0.01). Interestingly, several did not correlate, relationship, frequency intercourse, symptoms, direction curve, curvature, partner libido. Conclusions notable factors are (as assessed domain), equally importantly, surprisingly (e.g. curvature direction). These provide useful information practicing clinician help better identify may at greater risk condition. Disclosure No